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Results for "General Danger Signs / Very Severe Disease" (Age: 2 months - 5 years)

General Danger Signs / Very Severe Disease 2 months - 5 years

Refer URGENTLY High match
What to tell caregiver
  • Explain clearly to the mother/caregiver why referral is urgent and necessary.
  • Explain any pre-referral treatments given and why.
  • Advise on how to keep the child warm during transport (e.g., blanket, skin-to-skin).
  • Advise on continuing breastfeeding during transport if possible.
  • If the child also has dehydration, show how to give frequent sips of ORS on the way.
  • Write a referral note detailing assessment findings, classification, treatments given, and reason for referral.
Dosage Helper

Enter child weight (kg). Verify against local protocol before prescribing.

  • Rectal Diazepam: --
  • IM Ampicillin: --
  • IM Gentamicin: --

Identification of any life-threatening general danger sign in children aged 2 months to 5 years, indicating a Very Severe Disease requiring immediate urgent attention and pre-referral treatment before transport to a hospital.

Key Features
  • The presence of ANY ONE of the listed general danger signs classifies the child as having Very Severe Disease.
  • These signs indicate a life-threatening condition requiring immediate action and urgent referral, regardless of the main complaint.
Red Flags (Warning Signs)
  • Unable to drink or breastfeed
  • Vomits everything
  • History of convulsions during this illness
  • Convulsing now
  • Lethargic or unconscious
Assessment
Ask
  • Is the child able to drink or breastfeed?
  • Does the child vomit everything?
  • Has the child had convulsions during this illness?
Look, listen, feel
  • See if the child is lethargic or unconscious.
  • Is the child convulsing now?
Classification
  • Any general danger sign present (Unable to drink/breastfeed OR Vomits everything OR Had convulsions OR Lethargic/unconscious OR Convulsing now) -> VERY SEVERE DISEASE
Urgency / Refer urgently

Refer URGENTLY

Pre-referral treatment
  • If convulsing now: Give Diazepam rectally (10mg/2ml solution). Dose: <6m (<5kg) 0.5ml; 6-<12m (5-<10kg) 1.0ml; 1-<3y (10-<15kg) 1.5ml; 4-<5y (15-19kg) 2.0ml. If convulsions continue after 10 minutes, repeat the dose.
  • Treat to prevent low blood sugar: If child can breastfeed, ask mother to do so. If not able to breastfeed but able to swallow: Give expressed breast milk OR breastmilk substitute OR sugar water (Dissolve 4 level teaspoons (20g) sugar in 200ml clean water) - give 30-50ml before departure. If child not able to swallow: Give 50ml of milk or sugar water by nasogastric tube.
  • Give relevant pre-referral treatment based on quick assessment findings:
  • If signs of Severe Pneumonia/Serious Infection: Give first dose Intramuscular Ampicillin (50 mg/kg) AND Gentamicin (7.5mg/kg). Ampicillin doses (500mg vial diluted to 2.5ml): 4-<6kg: 1ml; 6-<10kg: 2ml; 10-<15kg: 3ml; 15-20kg: 5ml. Gentamicin doses (40mg/ml vial): 4-<6kg: 0.5-1.0ml; 6-<10kg: 1.1-1.8ml; 10-<15kg: 1.9-2.7ml; 15-20kg: 2.8-3.5ml.
  • If signs of Very Severe Febrile Disease/Suspected Severe Malaria: Give Rectal Artesunate (10 mg/kg, single dose) OR Intramuscular/IV Artesunate (3 mg/kg if =20kg) OR Intramuscular Quinine (refer to page 11 for detailed dosing based on concentration).
  • If signs of Severe Dehydration (Plan C): Start IV fluids immediately if possible OR if child can drink give ORS sips frequently on the way to hospital (refer to page 13).
Management
Non-Pharmacological Management
  • Quickly complete the assessment to identify all necessary pre-referral treatments.
  • Keep the child warm: Cover the child, ensure no draughts. If possible use skin-to-skin contact.
  • Position the child appropriately (e.g., recovery position if unconscious and not convulsing, clear airway).
Pharmacological Treatment
  • Specific pharmacological pre-referral treatments depend on associated classifications identified during the rapid assessment (see pre_referral section).
Monitoring & Follow-Up
  • To be managed at the referral hospital facility.
Counselling Points
  • Explain clearly to the mother/caregiver why referral is urgent and necessary.
  • Explain any pre-referral treatments given and why.
  • Advise on how to keep the child warm during transport (e.g., blanket, skin-to-skin).
  • Advise on continuing breastfeeding during transport if possible.
  • If the child also has dehydration, show how to give frequent sips of ORS on the way.
  • Write a referral note detailing assessment findings, classification, treatments given, and reason for referral.
Differential Diagnosis
  • Severe Pneumonia
  • Meningitis
  • Cerebral Malaria
  • Severe Dehydration with shock
  • Severe Sepsis
  • Severe Malnutrition with complications
  • Poisoning
  • Diabetic Ketoacidosis (rare)
Potential Complications
  • Shock (Septic, Hypovolemic)
  • Respiratory failure
  • Severe metabolic acidosis/electrolyte imbalance
  • Organ failure
  • Brain damage (from hypoxia, hypoglycemia, infection, convulsions)
  • Death
Prevention
  • Complete routine childhood immunizations.
  • Exclusive breastfeeding for the first 6 months, continued breastfeeding with appropriate complementary feeding.
  • Use of insecticide-treated nets (ITNs) in malaria-endemic areas.
  • Handwashing and safe water/sanitation.
  • Prompt recognition of illness and seeking appropriate care.
  • Good maternal health and nutrition.

Reference: IMCI Chart Booklet - Page 1, Pages 11-13

Features

IMCI Guidelines

Quickly access assessment, classification, and treatment guidance from the IMCI handbook.

Symptom Search

Search by condition name, keyword, or common symptoms such as fever, cough, or diarrhoea.

Age Groups

Separate guidance for young infants 0-2 months and children 2 months-5 years.

Red Flags

Identify urgent warning signs early and know when referral is needed.

Common Conditions Quick Access

Respiratory

Cough / Pneumonia

Guidance for assessing cough, difficult breathing, and classifying pneumonia severity.

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Gastrointestinal

Diarrhoea / Dehydration

Protocols for diarrhoea assessment, dehydration levels, and fluid management.

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Systemic

Fever / Malaria

Steps for managing fever, malaria testing, and treating febrile illness.

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Severe Illness

Danger Signs

Identify general danger signs that need urgent referral and immediate action.

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Important Disclaimer

This search tool is for informational and educational use by trained health workers using IMCI guidance. It is not a substitute for professional medical diagnosis, treatment, or emergency care. Parents and caregivers should seek qualified medical help immediately when a child is unwell.

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