An injection is a medical procedure where a needle and syringe are used to put a substance into the body. The substance can be a medicine, a vaccine, a contraceptive, or a fluid like blood or intravenous solution.
- Intravenous (IV): Into a vein
- Intramuscular (IM): Into a muscle
- Subcutaneous (SC): Under the skin
- Intradermal (ID): Into the skin layer
For nurses: Giving injections is one of the most common procedures you will perform. It is also one of the most dangerous if not done safely.
- About 95% of all injections worldwide are given to treat illnesses (therapeutic injections).
- About 3% are immunizations (vaccines to prevent disease).
- The remaining 2% are for other purposes like blood transfusions, contraceptives, or diagnostic tests.
In many developing countries, including Uganda, up to 9 out of 10 people who visit a primary health care provider receive an injection. However, more than 70% of these injections are unnecessary. The same treatment could have been given as a tablet, capsule, or liquid medicine that the patient swallows.
Every unnecessary injection is an unnecessary risk. It is a risk of:
- Infection (HIV, hepatitis)
- Needlestick injury to the nurse
- Waste that harms the community
- Wasted money and resources
Key Message: As a nurse, you must ask yourself: "Does this patient really need an injection, or can they take oral medication?" This is part of your professional responsibility.
When we talk about injection safety, we must protect three groups of people:
The patient must be protected from:
- Infections caused by dirty needles or syringes
- Contaminated medication
- Unsafe injection techniques
- Reactions to improperly stored vaccines
The nurse must be protected from:
- Needlestick injuries
- Exposure to bloodborne pathogens
- Accidental splashes of blood or body fluids
- Stress and anxiety from unsafe working conditions
The community must be protected from:
- Needles and syringes scattered in the environment
- Infectious waste contaminating water and soil
- Children and scavengers picking up used sharps
- Air pollution from burning medical waste
Remember: Safe injection practice is not just about the moment of giving the injection. It is about the entire journey—from deciding the patient needs an injection, to preparing it, giving it, and disposing of the waste safely.
According to the World Health Organization, a safe injection is one that:
- Does not harm the person receiving it
- Does not put the person giving it at unnecessary risk
- Does not create dangerous waste for the community
Think of it as a triangle:
- At the top is the patient (safe from infection)
- On the left is the health worker (safe from injury and infection)
- On the right is the community (safe from hazardous waste)
- In the center is proper technique and proper disposal
If any one of these three is missing, the injection is NOT safe.
Why: Reusing a syringe or needle, even once, can transfer bloodborne pathogens from one patient to another.
What this means:
- Never use the same syringe for two different patients, even if you change the needle.
- Never use the same needle for two different patients.
- If you draw medication from a vial for Patient A, you cannot use that same syringe to draw medication for Patient B.
Ugandan Context: In some under-resourced settings, there may be pressure to reuse syringes due to shortages. This is never acceptable. As a nurse, you must refuse. Patient safety and your own safety come before cost-saving.
What to do:
- Wash your hands before preparing injections.
- Clean the top of multi-dose vials with an alcohol swab before puncturing.
- Do not touch the needle or the inside of the syringe.
- Keep vaccines at the correct temperature (cold chain).
- Do not use vaccines that have expired, changed color, or have particles floating in them.
What to do:
- Prepare injections away from patient treatment areas if possible.
- Do not prepare injections in areas contaminated with blood or body fluids.
- Use a clean tray or surface.
- Do not prepare injections near open windows where dust can blow in.
- Do not prepare injections while wearing bloody gloves or while cleaning up waste.
What to do:
- Always use a new, sterile needle to enter a multi-dose vial.
- Do not use a needle that has already been used on a patient to enter a vial.
- Do not use a needle that has touched any non-sterile surface.
Why this is dangerous:
- The needle can bend or become contaminated.
- Someone might accidentally prick themselves.
- Medication can leak out.
- The needle can break off inside the stopper.
What to do: Remove the needle immediately after drawing the medication.
What is an ampoule? A small sealed glass container that holds medication.
How to open safely:
- Use a small gauze pad or cloth to hold the ampoule.
- Break the ampoule away from your body.
- Do not use bare fingers.
- Dispose of broken glass in a sharps container, not in general waste.
Examples of non-sterile contact:
- The needle touches your hand or finger.
- The needle touches the patient's bed, clothing, or skin before injection.
- The needle falls on the floor.
- The needle touches the outside of the vial.
What to do: Immediately discard the needle in a sharps container. Do not attempt to clean it or use it. Get a new one.
Why patients move suddenly:
- Fear of needles (especially children)
- Pain causing a reflex jerk
- Confusion or delirium
- Seizures
- Startle response
How to prepare:
- Explain the procedure to the patient.
- Position the patient comfortably and securely.
- Have an assistant hold children or confused patients.
- Keep your fingers away from the needle tip.
- Be prepared to withdraw the needle quickly if the patient moves.
This is one of the most important rules in nursing.
Why recapping is dangerous:
- Most needlestick injuries happen during recapping.
- The needle can slip and prick your finger.
- You cannot see the needle tip when recapping.
- It takes only a split second, but the consequences can last a lifetime (HIV, hepatitis).
What to do instead:
- Immediately place the used needle and syringe into a sharps container.
- If you absolutely must recap (which is rare and not recommended), use a one-handed scoop technique, but it is better to never recap at all.
What this means:
- The sharps container should be within arm's reach of where you are giving the injection.
- Do not walk across the room carrying a used needle.
- Do not put used needles on trays, beds, or tables.
- Dispose immediately after use.
When is a sharps container full?
When it is three-quarters (3/4) full. Never overfill. Overfilling causes needles to stick out and injure the next person.
What to do:
- Close and seal the container when it reaches 3/4 full.
- Label it with the date and location.
- Store it in a secure place until proper disposal.
- Never open, empty, or reuse a sealed sharps container.
What this means:
- Sharps containers must be disposed of in a way that does not harm the environment.
- Do not throw sharps containers into regular rubbish bins.
- Do not bury them in shallow pits where they can be dug up.
- Do not burn them in open fires.
- Follow your hospital's waste management protocol.
Who are waste handlers? Cleaners, waste collectors, incinerator operators, scavengers (people who pick through rubbish).
How to protect them:
- Properly seal all sharps containers.
- Label hazardous waste clearly.
- Train waste handlers on safety.
- Do not mix sharps with general waste.
Why:
- Glass vials can burst when burned in incinerators, sending sharp fragments flying.
- They take up space needed for actual sharps.
- They are not sharp and do not belong in sharps containers.
What to do: Empty vials go into general infectious waste or pharmaceutical waste containers, depending on your hospital policy.
Do NOT put in sharps containers:
- Empty vials
- Cotton swabs or gauze
- Packaging materials
- Gloves (unless bloody and your policy requires it)
- General rubbish
Only put in sharps containers:
- Used needles
- Used syringes
- Lancets
- Broken glass ampoules
- Scalpel blades
- Any other sharp medical items
- Hand hygiene before and after the procedure
- Use of sterile gloves when indicated
- Cleaning the injection site with antiseptic (usually 70% alcohol)
- Allowing the antiseptic to dry before injecting (do not blow on it)
- Using aseptic technique throughout
Even if you change the needle.
Why: The syringe barrel (the plastic tube) may be contaminated with blood. When you attach a new needle and draw medication, you can draw blood into the vial, contaminating it for the next patient.
This is a critical exam point: Changing the needle does NOT make a syringe safe for reuse.
Why: This contaminates the vial with blood and bacteria. The next patient who receives medication from that vial can become infected.
Examples:
- Ampoules meant for one patient
- Single-dose vials
- Pre-filled syringes
Even if there is leftover medication, do not save it for another patient. Discard it.
Why: The IV tubing and bag can become contaminated. Each patient must have their own IV solution bag and administration set.
Best practice: If a multi-dose vial is opened, label it with the patient's name, date, and time. Use it only for that patient.
If this is not possible: Follow your hospital's policy, but never use a multi-dose vial if the sterility is compromised.
Why: Patient areas have blood, body fluids, and airborne contaminants. Preparing medications there increases the risk of contamination.
What to do: Use a clean medication preparation room or a dedicated clean area.
When:
- Injecting material into the epidural space (spinal anesthesia)
- Placing a catheter into the subdural space
- Any procedure where there is risk of spraying or splashing
Why: To protect yourself from inhaling droplets or particles.
Unsafe injections occur because of:
- Lack of knowledge about safe injection practices
- Shortage of supplies (syringes, needles, sharps containers)
- Pressure to work quickly
- No supervision or accountability
- Reuse of equipment to save money
- Lack of policies and enforcement
- Regular training on injection safety
- Updates on new guidelines
- Competency assessments
- Refresher courses
- For nursing students: You are learning this now so that safe injection practice becomes automatic—a habit you never break.
- Senior nurses should supervise junior nurses and students.
- Spot-checks to ensure protocols are followed.
- Constructive feedback, not punishment.
- Written policies on injection safety
- Clear consequences for violations
- Regular audits of injection practices
- Reporting systems for unsafe practices
- Only trained, competent nurses should give injections.
- Verify qualifications before hiring.
- Do not allow untrained staff to administer injections.
- Never allow a student to give an injection unsupervised until they have demonstrated competence.
- The supervising nurse is responsible for the student's actions.
- Use this as a teaching moment, not just a task to get done.
Needlestick injuries are one of the most common and most dangerous occupational hazards for nurses. Preventing them is a top priority.
What are safety needles? Needles with built-in safety features that automatically cover or retract the needle after use.
Types:
- Retractable needles: The needle pulls back into the syringe after use.
- Shielded needles: A plastic shield slides over the needle after use.
- Blunt-tip needles: Used for certain procedures where a sharp tip is not necessary.
Benefits: Immediately reduces risk of needlestick, no need to recap, one-handed activation.
Challenges in Uganda: Safety needles are more expensive and may not be available in all facilities. However, nurses should advocate for their use. The cost of treating one HIV infection from a needlestick far exceeds the cost of safety needles.
- Never pass uncapped needles hand-to-hand.
- Never put needles in your pocket.
- Never point needles toward yourself or others.
- Do not bend, break, or manipulate needles after use.
- Dispose immediately after use.
Minimum PPE for giving injections:
- Clean gloves (sterile gloves for certain procedures)
- Gown if there is risk of splashing
- Facemask and eye protection for high-risk procedures
Remember: Gloves protect you, but they are not 100% effective. A needle can pierce a glove. Safe handling is still essential.
- Use puncture-resistant sharps containers.
- Place containers at the point of use.
- Do not overfill.
- Seal when 3/4 full.
- Replace immediately when sealed.
Examples:
- Needleless IV connectors
- Blunt cannulas for drawing medication
- Oral medication instead of injections when appropriate
Benefit: Eliminates the needle entirely, removing the risk.
What are engineering controls? Physical changes to the workplace or equipment that reduce risk.
Examples:
- Self-sheathing needles
- Retractable syringes
- Sharps disposal units built into medication carts
- Safety IV catheters
- All health workers must be trained on needle safety before they give injections.
- Training must be repeated regularly.
- New staff and students must receive orientation.
- Training must include what to do if a needlestick occurs.
A formal program that includes:
- Risk identification (where do needlesticks happen most?)
- Guidance and protocols
- Encouragement of reporting (no blame culture)
- Regular review of incidents
- Implementation of improvements
- Train all staff on proper disposal.
- Close and seal containers when full.
- Arrange regular collection and replacement.
- Do not let containers overflow.
- Do not leave full containers in patient areas.
- Place containers in every patient room.
- Place containers in medication preparation areas.
- Place containers in emergency trolleys.
- Make sure they are at a comfortable height.
- Ensure they are visible and easy to use.
- Do not rush disposal.
- Take a moment to ensure the needle goes safely into the container.
- Activate safety features before disposal.
- Do not leave used needles on trays or beds "just for a moment."
- Talk to your team about needle safety.
- Remind each other.
- If you see an unsafe practice, speak up respectfully.
- Create a culture where safety is everyone's responsibility.
For IV access, use needleless connectors and valves that do not require needles for flushing or connecting tubing.
Similar to safety needles, these syringes have features that reduce the risk of needlestick during injection or withdrawal.
- Stay updated on new safety technologies.
- Attend refresher training.
- Review and update protocols annually.
- Learn from incidents and near-misses.
Despite all precautions, needlestick injuries can still happen. Knowing exactly what to do can save your life.
| No. | Action | Details & Rationale |
|---|---|---|
| 1 | Stay Calm | Panic makes you rush and possibly make more mistakes. Take a deep breath. Remind yourself that immediate action reduces risk. |
| 2 | Allow Bleeding |
|
| 3 | Wash the Area |
|
| 4 | Cover the Wound | Apply a waterproof bandage or dressing. This protects the wound from further contamination. |
| 5 | Inform Your Supervisor Immediately | Tell your immediate supervisor or senior nurse right away. Do not wait until the end of your shift. Do not feel ashamed—needlestick injuries happen, and reporting is essential. |
| 6 | Report to Occupational Health | Go to your hospital's occupational health department. If there is no occupational health department, see the medical officer or infection control nurse. They will assess your risk and guide next steps. |
| 7 | Identify the Source Patient | If possible, find out which patient's blood was on the needle. This is critical for testing. Do not confront the patient aggressively. Your supervisor or doctor will handle the communication. |
| 8 | Collect Information | Document: Date and time of the injury, Type of device (needle, syringe, scalpel, etc.), How the injury happened, Whether the device had a safety feature, Whether the needle was hollow-bore or solid (hollow-bore needles carry higher risk), and Details about the source patient (if known). |
| 9 | Testing and Treatment |
|
| 10 | Follow Medical Recommendations | Take PEP exactly as prescribed. Do not skip doses. Complete the full 28-day course for HIV PEP. Follow up for repeat testing. |
| 11 | Document the Incident | Fill out an incident report form. Keep copies for your own records. Note all dates, times, tests, and treatments. This documentation is important for medical follow-up, workers' compensation, legal protection, and improving safety protocols. |
- 6 weeks after exposure
- 3 months after exposure
- 6 months after exposure
Important: Do not assume you are safe because you feel fine. Some infections have no early symptoms. Testing is the only way to know.
Used injection equipment is hazardous because it:
- Can transmit bloodborne infections
- Can cause needlestick injuries
- Can pollute the environment
- Can be scavenged and reused illegally
What it is: Digging a pit and burying waste, sometimes mixing it with cement, sand, or plaster to immobilize it.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: Small rural health centers with no other options, as a temporary measure.
What it is: Open burning or burning in simple drums at low temperatures.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: Emergency situations where no other method is available. Not recommended as a routine method.
What it is: Burning waste in an incinerator that reaches 800-1000 degrees Celsius.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: District hospitals with moderate waste volumes and trained staff.
What it is: Burning waste in advanced incinerators that reach over 1000 degrees Celsius, often with pollution control devices.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: Large referral hospitals and centralized waste treatment facilities.
What it is: Devices that cut, melt, or destroy needles. Range from simple manual devices to battery-operated or electrical units.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: Health centers that want to destroy needles on-site before final disposal.
What it is: Using heat to melt plastic syringes into a solid mass.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: Facilities with proper ventilation and electricity, as part of a larger waste management system.
What it is: Using high-pressure steam to sterilize waste, then shredding it to prevent reuse.
| Strengths | Weaknesses |
|---|---|
|
|
Best for: Larger hospitals with reliable electricity and water, and trained maintenance staff.
The best method depends on:
- Volume of waste: Small clinic vs. large hospital
- Resources available: Money, electricity, water, fuel
- Staff training: Can staff operate complex equipment?
- Environmental regulations: What does the law allow?
- Location: Urban vs. rural, water table level, rainfall
- Type of waste: Sharps only, or mixed infectious waste?
In Uganda: Many rural health centers use burial pits with cement encapsulation. Larger hospitals may have incinerators. The ideal is to move toward autoclaving and centralized waste treatment where possible.
- Many patients believe injections are stronger and work faster than tablets.
- Patients may demand injections because they believe oral medicine is "weak."
- In some communities, receiving an injection is seen as proof that the doctor/nurse has done something substantial.
- Nurse's role: Educate patients. Explain that oral medication is equally effective for many conditions and safer.
- Some health workers also believe injections are superior.
- They may give injections to satisfy patient expectations.
- They may not take time to explain why oral medication is appropriate.
- In some private facilities, injections cost more than tablets.
- Providers may prescribe unnecessary injections to increase income.
- This is unethical and dangerous.
- Some providers do not know that oral alternatives exist.
- They may not be up-to-date on treatment guidelines.
- They may follow outdated practices.
Unsafe injections can transmit:
- Hepatitis B
- Hepatitis C
- HIV/AIDS
These are life-threatening infections that can be prevented by using oral medication instead of unnecessary injections.
Even safe vaccines can cause:
- Local reactions (pain, swelling, redness)
- Fever
- Allergic reactions (rare but serious)
- Anaphylaxis (life-threatening allergic reaction)
Unnecessary injections increase the chance of these side effects.
Every unnecessary injection is an unnecessary risk of needlestick injury to the nurse.
Unnecessary injections create unnecessary hazardous waste that pollutes soil, air, and water.
If communities associate injections with disease transmission (because of unsafe practices), people may refuse vaccines. This reduces immunization coverage and allows preventable diseases to spread.
- Educate the public: Teach communities that tablets and syrups are often just as good.
- Train providers: Update health workers on when injections are truly necessary.
- Enforce guidelines: Ensure providers follow standard treatment guidelines.
- Monitor prescribing: Review prescription patterns to identify overuse.
- Make oral medications available: If oral drugs are out of stock, patients will demand injections.
- Empower nurses: Nurses should feel confident to question unnecessary injection orders.
Mass immunization campaigns (like polio vaccination, COVID-19 vaccination, or measles campaigns) create enormous amounts of injection waste in a short time. Special planning is needed.
Before the campaign:
- Estimate the number of injections to be given
- Calculate the volume of sharps waste expected
- Ensure enough sharps containers are available
- Arrange for collection and final disposal
- Train all vaccinators on safe disposal
- Identify disposal sites and methods in advance
- Dispose of sharps immediately at the vaccination site
- Do not transport full sharps containers long distances
- Seal containers when 3/4 full
- Replace containers immediately
- Keep a log of waste generated
- Ensure all waste is properly disposed of
- Do not leave waste at temporary sites
- Conduct an audit of waste management
- Document lessons learned for future campaigns
A mother brings her 3-year-old child to the health center with a mild cough and runny nose. The clinical officer prescribes an injection of antibiotics. The mother expects an injection because "injections work faster." You are the nurse. You know this is likely a viral infection that does not need antibiotics at all, and if treatment is needed, oral medication would be sufficient.
Discussion Questions:
- What are the risks of giving this unnecessary injection?
- How would you explain to the mother that oral medication is better?
- What would you do if the clinical officer insists on the injection?
- How does this scenario relate to injection overuse in Uganda?
Nurse Okello is working alone in a busy outpatient department. He has 50 patients waiting. He gives an injection to a patient with unknown HIV status. In his hurry to see the next patient, he tries to recap the needle. The needle slips and pricks his thumb. He is terrified but has 40 more patients to see.
Discussion Questions:
- What should Nurse Okello do in the next 10 minutes?
- What are his risks of HIV and hepatitis infection?
- How could this have been prevented?
- What does this scenario teach us about staffing and safety?
- What PEP protocol should be followed?
Your district is conducting a measles vaccination campaign. You are stationed at a rural health center. You expect to vaccinate 500 children in three days. You have been given 500 syringes and needles, but only two sharps containers. There is no incinerator at your facility. The nearest district hospital is 50 kilometers away.
Discussion Questions:
- How many sharps containers do you actually need? (Answer: At least 10-15, since each container holds about 50-70 syringes when filled to 3/4)
- What will you do when the sharps containers are full?
- How will you transport sealed containers to the district hospital safely?
- What disposal method would be most appropriate if transport is impossible?
- What are the infection risks to your community if waste is not managed properly?
Nurse Amina is preparing vaccinations for five children. She uses the same needle to draw vaccine from the multi-dose vial for all five children. She changes the needle between each child but uses the same syringe. On the third child, she accidentally touches the needle to the child's dirty clothing. She changes the needle and continues.
Discussion Questions:
- What did Nurse Amina do wrong?
- What is the risk of using the same syringe for multiple patients, even with needle changes?
- What is the risk of touching the needle to clothing?
- How should she have prepared the vaccines?
- What infections could be transmitted?
- New syringe and needle for each patient
- Equipment kept clean
- Wash hands
- Clean area for preparation
- Leave needle out of vial stopper
- Encapsulate? NO! Never recap
- Ampoules opened with gauze protection
- Non-sterile contact = discard needle
- Sudden patient movement—be ready
- All sharps disposed at point of use
- Full containers sealed at 3/4
- Environmental safety in disposal
- Do not put empty vials in sharps boxes
- Infection control practices always
- Same syringe never for two patients
- Put used needles straight into safety box
- Only contaminated sharps in safety boxes
- Source patient identified after needlestick
- Expose wound, wash, report
- Bleed the wound gently
- Let it flow (don't suck)
- Expose and wash with soap and water
- Wash for 20 seconds
- Apply waterproof dressing
- Supervisor informed immediately
- Head to occupational health
- Record all details
- Expose source patient for testing
- PEP started ASAP (within 2 hours best, 72 hours max)
- Ongoing follow-up testing at 6 weeks, 3 months, 6 months
- Report incident formally
- Take medications exactly as prescribed
- Test baseline and follow-up
- Report
- Educate others to prevent recurrence
- All documentation kept
- Test baseline and follow-up
- Recipient safe
- Provider safe
- Community safe
- Belief that injections are stronger
- Financial gain for providers
- Patient demand and preference
- Know the WHO definition of a safe injection by heart. It protects three groups: recipient, provider, and community.
- Never recap a used needle. This is the most common cause of needlestick injuries and is always tested.
- Changing the needle does NOT make a syringe safe for reuse. The syringe barrel can be contaminated with blood.
- A sharps container is full at 3/4 capacity. Never overfill. This is a common exam question.
- Know the PEP timeline: HIV PEP must start within 72 hours, ideally within 2 hours. Hepatitis B needs immunoglobulin and vaccine if not immune.
- Multi-dose vials: Use a new sterile needle to enter. Do not leave the needle in the stopper. Label with date and patient name if possible.
- Injection overuse in developing countries: Remember the statistic—up to 90% of primary care patients may receive injections, and over 70% may be unnecessary.
- Waste disposal methods: Know the strengths and weaknesses of burial pits, burning, incineration, and autoclaving. Know which is appropriate for which setting.
- Safety needles and needleless systems: These are engineering controls that reduce needlestick risk. Be able to name examples.
- The nurse's role in preventing overuse: Nurses can educate patients, question unnecessary orders (professionally), and advocate for oral alternatives.
- Documentation after needlestick: Always document. It protects you legally and medically.
- In mass immunization: Plan waste disposal BEFORE the campaign starts. Running out of sharps containers during a campaign is a disaster.
- Empty vials do NOT go in sharps containers. They can burst during incineration and send glass flying.
- Hand hygiene is part of injection safety. Clean hands before preparing injections, even if you will wear gloves.
- Remember the connection to disaster management: Unsafe injections can cause disease outbreaks (HIV, hepatitis). Mass immunization campaigns without proper waste management create environmental disasters. Injection safety IS disaster prevention.
- World Health Organization (WHO). (2010). WHO best practices for injections and related procedures toolkit.
- World Health Organization (WHO). (2005). Guiding principles to ensure injection device security.
- Centers for Disease Control and Prevention (CDC). Injection Safety Guidelines and Infection Control Standard Precautions.
- Uganda Ministry of Health. National Infection Prevention and Control Guidelines.
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Injection Safety Quiz
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